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Crohn’s Disease Trials

Currently recruiting

SPECIFI (Sanofi)

A phase 2, multinational, multicenter, randomized, double-blind, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of SAR441566 in adults with moderate to severe Crohn's disease. 

Currently recruiting

TARGET (Abbvie)

A Phase 2a multicenter, randomized, platform study of targeted therapies for the treatment of adult subjects with moderate to severe crohn's disease involving risankizumab, ABBV-382, and litikizumab.    

Currently recruiting

COMMIT (Eli Lilly)

A Phase 3b, randomized, multicenter, controlled study of mirikizumab and placebo or mirikizumab concomitantly administered with tirzepatide in adult participants with moderately to severely active Crohn's disease and obesity or overweight.

Currently recruiting

CHARGE (Janssen)

A Phase 3b, randomized, multicenter, open-label, active-controlled study to compare the efficacy and safety of guzelkumab versus risankizumab in the treatment of participants with moderately to severely active Crohn's disease. 

Coming soon

DUET ENCORE (Janssen)

Phase 2b Randomized, double-blind, active-and placebo-controlled, parallel-group, multicenter study to evaluate the efficacy and safety of induction and maintenance combination therapy with guselkumab and golimumab in participants with moderately to severely active crohn's disease.

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